|
|
|
|
|
5th Muharram 1436 | Saturday, Nov 01, 2014
Health

Arthritis drugs may help cure Alzheimer’s

Thursday, 20 December 2012
Comments(0)
London, December 20:

Experts believe drugs for arthritis could also be used to treat dementia.

Doctors have found that inflammation linked to the painful joint condition plays an important role in triggering the deadly brain disease.

The inflammation boosts production of toxic cells in the brain called plaques.

“With this link, we have a new path to potentially identifying and attacking this horrible disease,” the Daily Express quoted the leader of the research, Dr Douglas Golenbock, as saying.

One expert said the evidence could lead to the “Holy Grail” in the study of the disease.

“As current treatments merely stabilise the condition, finding ways to stop the physical causes building up in the first place is the Holy Grail for researcher,” said Jess Smith, of the Alzheimer’s Society.

“Studying how the brain protects itself from injury is helping us reach that goal. The next step is to explore how drugs for inflammation and arthritis could be used to combat the condition. One in three people over 65 will develop dementia. Identifying already existing drugs which could be used to treat dementia is vital to get new treatments on the shelf in a fraction of the time it takes to develop drugs from scratch,” Smith added.

The study found that an immune process in the body sparks the production of a protein called interleukin-1 beta (IL-1B).

This protein is involved in the body’s defence against infection and has also been pinpointed as a drug target for rheumatoid arthritis – which occurs when the immune system attacks joints, causing pain and inflammation.

The study, published in the journal Nature, points to the possibility that drugs that disrupt the production of IL-1B, such as those for rheumatoid arthritis, may also benefit Alzheimer’s patients.

Previously, brain inflammation in Alzheimer’s sufferers was thought to be a side effect. But increasing scientific evidence suggests that it might be a primary cause, raising the possibility of fighting Alzheimer’s with common anti-inflammatories such as aspirin and ibuprofen.

The latest study examined the destructive amyloid beta plaques, which are a hallmark of Alzheimer’s, clumping together in the brain and destroying it, leading to memory loss and confusion.

“The findings are still at an early stage but research into inflammation in Alzheimer’s is an important area for the future,” said Dr Simon Ridley, of Alzheimer’s Research UK. (ANI)

Latest News

Security situation has improved in Northeast, says US Consul General

US Consul General in Kolkata, Helen Lafave, who recently visited Tripura, said that the security sit ...

Berdych secures place in Tour Finals post reaching Paris Masters semis

Czech tennis ace Tomas Berdych beat South African's Kevin Anderson in the quarterfinals of the Paris ...

Iranian ship detained in Gujarat

An Iranian ship has been detained at Essar jetty in Hajira port for its alleged involvement in an accident with a fishin ...

Related News

Satellites helping fight against Ebola for first time ever

British built satellites are now being used for the first time ever to help fight against the Ebola ...

Fitness sector witnesses growth in Manipur

The trend of working out in gyms is fast catching up with the people of Manipur. As people increasin ...

Punjab chemists to lose licence for selling banned drugs

Tightening the noose around medical practitioners and chemist shop owners who prescribe and sell ill ...

Post new comment

To combat spam, please enter the code in the image.

Rs. 26810 (Per 10g)

Opinion Poll
Do you think formation of 'She' teams would be beneficial for women's safety?
YesNoCan't say

Matrimony | Photos | Videos | Search | Polls | Archives | Advertise | Letters

© The Siasat Daily, 2012. All rights reserved.
Jawaharlal Nehru Road, Abids, Hyderabad - 500001, AP, India
Tel: +91-40-24744180, Fax: +91-40-24603188
contact@siasat.com