|
|
|
|
|
6th Zulqada 1435 | Tuesday, Sep 02, 2014
Health

Arthritis drugs may help cure Alzheimer’s

Thursday, 20 December 2012
Comments(0)
London, December 20:

Experts believe drugs for arthritis could also be used to treat dementia.

Doctors have found that inflammation linked to the painful joint condition plays an important role in triggering the deadly brain disease.

The inflammation boosts production of toxic cells in the brain called plaques.

“With this link, we have a new path to potentially identifying and attacking this horrible disease,” the Daily Express quoted the leader of the research, Dr Douglas Golenbock, as saying.

One expert said the evidence could lead to the “Holy Grail” in the study of the disease.

“As current treatments merely stabilise the condition, finding ways to stop the physical causes building up in the first place is the Holy Grail for researcher,” said Jess Smith, of the Alzheimer’s Society.

“Studying how the brain protects itself from injury is helping us reach that goal. The next step is to explore how drugs for inflammation and arthritis could be used to combat the condition. One in three people over 65 will develop dementia. Identifying already existing drugs which could be used to treat dementia is vital to get new treatments on the shelf in a fraction of the time it takes to develop drugs from scratch,” Smith added.

The study found that an immune process in the body sparks the production of a protein called interleukin-1 beta (IL-1B).

This protein is involved in the body’s defence against infection and has also been pinpointed as a drug target for rheumatoid arthritis – which occurs when the immune system attacks joints, causing pain and inflammation.

The study, published in the journal Nature, points to the possibility that drugs that disrupt the production of IL-1B, such as those for rheumatoid arthritis, may also benefit Alzheimer’s patients.

Previously, brain inflammation in Alzheimer’s sufferers was thought to be a side effect. But increasing scientific evidence suggests that it might be a primary cause, raising the possibility of fighting Alzheimer’s with common anti-inflammatories such as aspirin and ibuprofen.

The latest study examined the destructive amyloid beta plaques, which are a hallmark of Alzheimer’s, clumping together in the brain and destroying it, leading to memory loss and confusion.

“The findings are still at an early stage but research into inflammation in Alzheimer’s is an important area for the future,” said Dr Simon Ridley, of Alzheimer’s Research UK. (ANI)

Latest News

Top militant commander among three killed in Kashmir gunfight

Three separatist guerrillas of the Jaish-e-Muhammad (JeM) outfit were Tuesday killed in a gunfight w ...

Amid questions raised over a reported tie-up between the IRCTC - a public sector enterprise under th ...

Second beheading plunges Obama into top crisis

Just two weeks after beheading American photojournalist James Foley, the Islamic State (IS) Sunni ex ...

Related News

AIIMS sees increase in eye donors

The eye bank of AIIMS has seen a rise in the number of donors in the last couple of years, an official said Tuesday. ...

Fear grips onlookers as Ebola victim walks through market

A video footage has emerged from Liberia showing a person tagged positive for Ebola virus disease (E ...

Kala-azar free India by 2015: Harsh Vardhan

Health Minister Harsh Vardhan Monday said that India aims to eliminate dreaded vector-borne disease ...

Post new comment

CAPTCHA
This question is for testing whether you are a human visitor and to prevent automated spam submissions.
Image CAPTCHA
Copy the characters (respecting upper/lower case) from the image.

Rs. 27530 (Per 10g)

Opinion Poll
Do you think KCR would continue celebrating all national events at Golconda Fort beginning from Independence Day?
YesNoCan't say

Comments >>

Matrimony | Photos | Videos | Search | Polls | Archives | Advertise | Letters

© The Siasat Daily, 2012. All rights reserved.
Jawaharlal Nehru Road, Abids, Hyderabad - 500001, AP, India
Tel: +91-40-24744180, Fax: +91-40-24603188
contact@siasat.com