|
|
|
|
|
4th Zilhaj 1435 | Wednesday, Oct 01, 2014
Health

HIV infected people may have increased heart attack risk

Tuesday, 5 March 2013
Comments(0)
March 05:

Washington, March 5 (ANI): Infection with the human immunodeficiency virus (HIV) was associated with an increased risk of acute myocardial infarction (AMI, heart attack), a new study has found.

Due to the successful antiretroviral therapy (ART), people infected with HIV are living longer and are at risk for heart disease, researchers said.

Matthew S. Freiberg, M.D., M.Sc., of the University of Pittsburgh School of Medicine, and colleagues examined whether HIV infection was associated with an increased risk of AMI after adjusting for standard Framingham risk factors in a large group of HIV-positive veterans and a similar group of uninfected veterans.

Researchers, who analyzed data from 82,459 study participants, found that during a median follow-up of 5.9 years there were 871 AMI events.

"Across three decades of age, the mean … AMI events per 1,000 person-years was consistently and significantly higher for HIV-positive compared with uninfected veterans," according to the study results.

The results indicate that for veterans ages 40 to 49 years, the events per 1,000 person-years were 2.0 for HIV-positive veterans vs. 1.5 for uninfected veterans; for those ages 50 to 59 years, 3.9 vs. 2.2; and for those ages 60 to 69 years, 5.0 vs. 3.3.

After adjusting for Framingham risk factors, co-existing illnesses and substance use, HIV-positive veterans had an increased risk of incident AMI compared with uninfected veterans (hazard ratio, 1.48), according to the results.

The study also noted that an "excess risk" remained among those achieving an HIV-1 RNA level less than 500 copies/mL compared with uninfected veterans (hazard ratio, 1.39).

Researchers noted that the study''s findings might not be generalizable to women because the group of patients studied was overwhelmingly male.

"In conclusion, HIV infection is independently associated with AMI after adjustment for Framingham risk, comorbidities and substance use. Unsuppressed HIV viremia, low CD4 cell count, Framingham risk factors, hepatitis C virus, renal disease and anemia are also associated with AMI," the study concluded.

The finding was published Online First by JAMA Internal Medicine, a JAMA Network publication. (ANI)

Latest News

Australian PM labels burqa 'confronti...

Australia's parliament approved tough new counter-terrorism laws Wednesday but cross-party support for the measures was accompanied a spat o ...

Modi's US visit disappointing on outcomes: Congress

Congress today launched an all-out attack on Prime Minister Narendra Modi, saying his US visit was " ...

Indo-US heat on Dawood Ibrahim

Dawood Ibrahim, the mastermind of the 1993 Mumbai blasts, and his financial network are now for the first time the targe ...

Related News

Viagra could affect vision: study

An active ingredient in the anti-impotence drug Viagra could cause unusual visual responses in people who carry a common ...

Fat tongue may be a factor in sleep apnea

A significantly larger tongue with a higher percentage of fat may be a sign of obstructive sleep apn ...

Deceased medic's parents get Rs. 27,2...

Twelve years after a 19-year-old medical student was crushed under the wheels of a truck in Ahmedabad, the Supreme Court has awarded compens ...

Post new comment

To combat spam, please enter the code in the image.

Rs. 26690 (Per 10g)

Opinion Poll
Do you think Satya Nadella's meeting with KCR is a booster for IT in Telangana state?
YesNoCan't say

Matrimony | Photos | Videos | Search | Polls | Archives | Advertise | Letters

© The Siasat Daily, 2012. All rights reserved.
Jawaharlal Nehru Road, Abids, Hyderabad - 500001, AP, India
Tel: +91-40-24744180, Fax: +91-40-24603188
contact@siasat.com