|
|
|
|
|
13th Jamadi-ul-Awwal 1436 | Friday, Mar 06, 2015
Health

Protein behind dry and scaly skin in eczema discovered

Monday, 7 January 2013
Comments(0)
London, January 07:

Scientists including an Indian-origin researcher have discovered a malfunctioning protein that triggers dry, itchy and inflamed skin lesions in a common type of eczema.

Researchers at Oregon State University found that the protein Ctip2 that controls body fats that keep skin healthy and hydrated, can cause atopic dermatitis, a common type of eczema if it is not performing properly.

Eczema allows significant loss of fluids through the skin, allowing allergens to penetrate, the `Daily Mail` reported.

"In these studies, we`ve basically shown that inadequate Ctip2 is reducing the lipids in skin that it needs to stay healthy, protect itself and perform its function," Arup Indra, an associate professor in the OSU College of Pharmacy said.

"At the same time, this can allow unwanted formation of proteins that trigger inflammation," Indra said.

"The skin`s ability to resist inflammation is going down just as the amount of inflammation is going up, and the underlying reason is that Ctip2 is not doing its job. Either or both of these problems can lead to eczema," Indra added.

Atopic dermatitis is associated with a dysfunctional immune response, but researchers have not understood the underlying cause.

Existing treatments use moisturisers to try to protect skin, and in difficult cases powerful steroid drugs can help, but they often have significant unwanted side effects, especially in long-term use.

Most people outgrow it as they reach adulthood, but some suffer from the condition their entire life.

"Our skin is the largest organ in the human body and one of the most important," Indra said.

"It`s our first barrier of defence, is in a constant battle against external insults, is influenced by both genetics and the environment, and has to be finely tuned to do many jobs. In eczema, this process begins to break down," Indra added.

The study was published in journal PLoS ONE.

PTI

Latest News

Arvind Kejriwal undergoes nature cure trea...

Delhi Chief Minister Arvind Kejriwal was today given massages and treated with abdomen pack as he underwent nature cure treatment for the se ...

Over 5,500 challaned for traffic violations in Delhi on Holi

More than 5,500 people were fined for violating traffic rules by Delhi Traffic Police today on the o ...

Maharashtra reconstitutes panel on border dispute with Karnataka

Maharashtra government has said it had reconstituted a high powered committee on the Maharashtra-Kar ...

Related News

Swine flu detected in Manipur

A woman in Manipur on Friday was detected with swine flu, the first case of this season to be found in the North Eastern state. According ...

Grandmother gives birth to her own granddaughter!

It may sound strange but it's true that a 61-year-old woman, late last year, gave birth to her own g ...

Swine flu claims 13 more lives in Guj; death toll reaches 324

Swine flu claimed 13 more lives in Gujarat today, taking the toll to 324 since January, an official ...

Post new comment

To combat spam, please enter the code in the image.

Rs. (Per 10g)

Opinion Poll
Do you think the dharna against Modi Government's land ordinance would be successful?
YesNoCan't say

Matrimony | Photos | Videos | Search | Polls | Archives | Advertise | Letters

© The Siasat Daily, 2012. All rights reserved.
Jawaharlal Nehru Road, Abids, Hyderabad - 500001, Telangana, India
Tel: +91-40-24744180, Fax: +91-40-24603188
contact@siasat.com