|
|
|
|
|
3rd Safarul Muzaffer 1436 | Thursday, Nov 27, 2014
Health

Protein behind dry and scaly skin in eczema discovered

Monday, 7 January 2013
Comments(0)
London, January 07:

Scientists including an Indian-origin researcher have discovered a malfunctioning protein that triggers dry, itchy and inflamed skin lesions in a common type of eczema.

Researchers at Oregon State University found that the protein Ctip2 that controls body fats that keep skin healthy and hydrated, can cause atopic dermatitis, a common type of eczema if it is not performing properly.

Eczema allows significant loss of fluids through the skin, allowing allergens to penetrate, the `Daily Mail` reported.

"In these studies, we`ve basically shown that inadequate Ctip2 is reducing the lipids in skin that it needs to stay healthy, protect itself and perform its function," Arup Indra, an associate professor in the OSU College of Pharmacy said.

"At the same time, this can allow unwanted formation of proteins that trigger inflammation," Indra said.

"The skin`s ability to resist inflammation is going down just as the amount of inflammation is going up, and the underlying reason is that Ctip2 is not doing its job. Either or both of these problems can lead to eczema," Indra added.

Atopic dermatitis is associated with a dysfunctional immune response, but researchers have not understood the underlying cause.

Existing treatments use moisturisers to try to protect skin, and in difficult cases powerful steroid drugs can help, but they often have significant unwanted side effects, especially in long-term use.

Most people outgrow it as they reach adulthood, but some suffer from the condition their entire life.

"Our skin is the largest organ in the human body and one of the most important," Indra said.

"It`s our first barrier of defence, is in a constant battle against external insults, is influenced by both genetics and the environment, and has to be finely tuned to do many jobs. In eczema, this process begins to break down," Indra added.

The study was published in journal PLoS ONE.

PTI

Latest News

Police register 165 FIRS during trade fair

Delhi Police registered 165 FIRs during this year's India International Trade Fair (IITF) under various cognisable sections of IPC, which ma ...

Attendants in Niloufer Hospital left in th...

Niloufer Hospital is one of the oldest hospitals of the city which is the institute of child health. With commercialization of medical profe ...

Dwarka water crisis: HC directs Haryana to release water

The Delhi High Court Thursday directed the Haryana government to release 719 cubic feet per second o ...

Related News

HP health panel stresses on need for good ...

The recently set up Himachal Pradesh Health Commission today held its first meeting here today and drew up a roadmap for improvement of heal ...

Not closing down operations in Baluchistan...

The World Health Organisation (WHO) today dismissed reports that it was suspending operations in Pakistan's troubled Baluchistan province fo ...

External artificial pancreas treatment more effective for diabetics than...

A new study has revealed that the external artificial pancreas improves glucose control and reduces ...

Post new comment

To combat spam, please enter the code in the image.

Rs. 26230 (Per 10g)

Opinion Poll
Do you think introduction of grills to separate ladies and gents in RTC buses add to travel woes?
YesNoCan't say

Matrimony | Photos | Videos | Search | Polls | Archives | Advertise | Letters

© The Siasat Daily, 2012. All rights reserved.
Jawaharlal Nehru Road, Abids, Hyderabad - 500001, Telangana, India
Tel: +91-40-24744180, Fax: +91-40-24603188
contact@siasat.com