|
|
|
|
|
13th Jamadi-ul-Awwal 1436 | Friday, Mar 06, 2015
Health

`Villain` stomach bug may help control diabetes

Saturday, 9 February 2013
Comments(0)
Washington, February 09:

A stomach bacterium which is believed to cause health problems such as gastritis, ulcers, and gastric cancer may play a dual role by balancing the stomach`s ecosystem and controlling body weight and glucose tolerance, researchers have claimed.

Usually the villain in studies of gastric cancer and peptic ulcers, Helicobacter pylori infect about half of the world`s population although most infected individuals don`t get sick.

The bacterium`s dwindling numbers coincide with the epidemic of obesity and diabetes in developed countries.

"H. pylori is the dominant member of the gastric microbiota and infects about half of the world population. While H. pylori infection can be associated with severe disease, it helps control chronic inflammatory, allergic, or autoimmune diseases," Josep Bassaganya-Riera, director of the Nutritional Immunology and Molecular Medicine Laboratory and the Center for Modeling Immunity to Enteric Pathogens (MIEP) at Virginia Tech said.

"We demonstrated for the first time that gastric colonization with H. pylori exerts beneficial effects in mouse models of obesity and diabetes," he said.

During the past 20 years, obesity in the United States has increased dramatically, according to the Centers for Disease Control and Prevention.

About 36 percent of US adults and approximately 17 percent of young people aged 2 to 19 years are obese. Obesity is the leading risk factor for type 2 diabetes and the rates of diabetes have increased in parallel with the rates of obesity.

Mice infected with H. pylori showed less insulin resistance than uninfected mice or other mice infected with a more virulent strain of H. pylori, according to the study.

Researchers believe that whether the infection is harmful or beneficial depends on the interaction between the genetic makeup of H. pylori and the host`s immune response.

H. pylori carrying the cytotoxin-associated gene pathogenicity island were harmful. But the bacteria with or without an atypical island may be integral to human stomach microbiota.

Indeed, studies show that humans have been colonized by H. pylori for about 116,000 years.

The role of H. pylori as a pathogen does not provide an explanation as to why it has colonized the stomach of humans thousands of years.

"Our new findings suggest that H. pylori may provide important metabolic traits required to ameliorate diabetes that humans have not evolved on their own," Bassaganya-Riera said.

This suggests that the overuse of antibiotics for everything from misdiagnosed infections in humans to supplementary livestock feed may destroy beneficial bacteria and contribute directly to diseases such as obesity, allergies, inflammatory bowel disease, and asthma.

It may be time for humans to reconsider how we can better co-exist with H. pylori and other microbes as a means of promoting health.

The findings are published in the journal PLOS One.

ANI

Latest News

Kim Kardashian steals attention with mesh dress

Reality TV star Kim Kardashian, who has revealed her platinum blonde locks, ensured all eyes were on ...

'Windies cricket problems mirror cris...

The problems hampering West Indies cricket mirror a crisis plaguing the Caribbean community, St. Lucia Prime Minister Kenny Anthony said. ...

'Dirty politics' in AAP?

For the Aam Admi Party (AAP) to begin falling apart less than a month after its famous victory in the Delhi election wil ...

Related News

Pro-veggie diet helps lower risk of heart disease, stroke

Semi-veggie diet, where proportion of plant-based foods is higher compared to animal-based foods, ca ...

LSD, magic mushrooms do not affect mental health

Psychedelics like LSD and magic mushrooms, do not put a person at risk of developing mental health p ...

WHO recommends annual vaccination to combat swine flu

Annual vaccination is the most effective solution for combating seasonal influenza infections such a ...

Post new comment

To combat spam, please enter the code in the image.

Rs. 26460 (Per 10g)

Opinion Poll
Do you think the dharna against Modi Government's land ordinance would be successful?
YesNoCan't say

Matrimony | Photos | Videos | Search | Polls | Archives | Advertise | Letters

© The Siasat Daily, 2012. All rights reserved.
Jawaharlal Nehru Road, Abids, Hyderabad - 500001, Telangana, India
Tel: +91-40-24744180, Fax: +91-40-24603188
contact@siasat.com