|
|
|
|
|
6th Zulqada 1435 | Tuesday, Sep 02, 2014
Health

Vitamin D reduces the risk of developing autism

Tuesday, 18 December 2012
Comments(0)
Washington, December 18:

Researchers have found additional evidence that vitamin D reduces the risk of developing autism by half.

The study examined the variation of autism prevalence by state in the US for those aged 6-17 years in 2010. It found that states with higher solar ultraviolet-B (UVB) doses in summer or autumn had half the rate of autism as states with the lowest.

Similar geographical variations have been noted for incidence and mortality rates for about 15 types of cancer in the US, `vitamin D council` reported.

One of the mechanisms whereby vitamin D might reduce the risk of autism is through reducing the risk of sporadic DNA mutations from influencing fetal development.

Another is through reducing the risk of influenza and other infectious diseases during pregnancy, which have been linked to increased risk of schizophrenia. Also, vitamin D reduces inflammation by shifting cytokine production towards less inflammatory cytokines.

If vitamin D deficiency during pregnancy is a risk factor for autism, then risk could be reduced by having pregnant women take 4000 IU/d vitamin D3 and raising serum 25(OH)D concentrations to above 40 ng/ml (100 nmol/l).

This amount has been shown to be both safe and necessary to increase concentrations of 1,25-dihydroxyvitamin D (calcitriol), the active metabolite of vitamin D, to optimal levels in a randomised controlled trial by Bruce Hollis, Carol Wagner and colleagues at the Medical University of South Carolina.

Vitamin D deficiency in early life could be a risk factor for autism, although this remains to be proved.

Vitamin D also strengthens the body`s innate immune system by inducing production of cathelicidin and defensins, which can combat bacterial and viral infections. It shifts cytokine production away from T-helper 1 (Th1) proinflammatory ones toward Th2 cytokines.

Recent studies also show vitamin D increases neurotrophins, upregulates glutathione, increases DNA repair enzymes, and protects against mitochondrial damage.

Once autism develops, symptoms may be reduced by treating vitamin D deficiency in autistic children, the study found.

The study was published in the peer-reviewed journal Dermato-Endocrinology.

PTI

Latest News

11 killed in China landslides

At least 11 people were killed and 27 others were missing Tuesday after heavy rains caused landslides in China's Chongqing province. Acc ...

Finance Minister Arun Jaitley undergoes su...

Finance Minister Arun Jaitley on Tuesday underwent a successful laparoscopic procedure at a hospital here. "Arun Jaitley underwent a plan ...

President prays at Vaishno Devi temple

President Pranab Mukherjee Tuesday prayed at the Mata Vaishno Devi temple here. The president signed the visitors' book and waved to the ...

Related News

`Beer belly` can increase hypertension risk

A new study had discovered that people with belly fat face more risk of developing hypertension than the ones who are obese overall. Obesit ...

Scientists discover new detect malaria parasite

Scientists have revealed a new way to use magnetic resonance relaxometry (MRR), a close cousin of ma ...

Sugar substance cuts down 'good' HDL cholesterol from body

A new research has discovered that "good" High Density Lipoprotein (HDL) cholesterol gets converted ...

Post new comment

CAPTCHA
This question is for testing whether you are a human visitor and to prevent automated spam submissions.
Image CAPTCHA
Copy the characters (respecting upper/lower case) from the image.

Rs. 27530 (Per 10g)

Opinion Poll
Do you think KCR would continue celebrating all national events at Golconda Fort beginning from Independence Day?
YesNoCan't say

Comments >>

Matrimony | Photos | Videos | Search | Polls | Archives | Advertise | Letters

© The Siasat Daily, 2012. All rights reserved.
Jawaharlal Nehru Road, Abids, Hyderabad - 500001, AP, India
Tel: +91-40-24744180, Fax: +91-40-24603188
contact@siasat.com