Washington: Long periods of time spent in space will require travellers to engage in high-intensity exercise to maintain their heart health, according to a new study.
The findings of the study were published in the American Heart Association’s flagship journal Circulation.
As NASA seeks to build a lunar outpost, visit Mars and commercialise spaceflight, the long-term effects of weightlessness on the human heart are of critical importance, according to researchers.
By analysing data from astronaut Scott Kelly’s year in space and comparing it to information from extreme long-distance, which simulates weightlessness, swimming of Benoit Lecomte, researchers found that low-intensity exercise was not enough to counteract the effects of prolonged weightlessness on the heart. Each time a person sits or stands, gravity draws blood into the legs.
The work the heart does to keep blood flowing as it counters Earth’s gravity helps it maintain its size and function. Removing gravitational effects causes the heart to shrink.
Researchers examined data from retired astronaut Scott Kelly’s stint aboard the International Space Station from 2015 to 2016 and elite endurance swimmer Benoit Lecomte’s swim across the Pacific Ocean in 2018. In this new study, researchers evaluated the effects of long-term weightlessness on the structure of the heart and to help understand whether extensive periods of low-intensity exercise can prevent the effects of weightlessness.
“The heart is remarkably plastic and especially responsive to gravity or its absence. Both the impact of gravity as well as the adaptive response to exercise play a role, and we were surprised that even extremely long periods of low-intensity exercise did not keep the heart muscle from shrinking,” said Benjamin D. Levine, M.D., the study’s senior author and a professor of internal medicine at UT Southwestern Medical Center and director of Texas Health Presbyterian’s Institute for Exercise and Environmental Medicine, both in Dallas.
The research team examined the health data of Kelly’s year in space aboard the International Space Station and Lecomte’s swim across the Pacific Ocean to investigate the impact of long-term weightlessness on the heart.
Water immersion is an excellent model for weightlessness since water offsets gravity’s effects, especially in a prone swimmer, a specific swimming technique used by long-distance endurance swimmers.
Kelly exercised six days a week, one to two hours per day during his 340 days in space, from March 27, 2015, to March 1, 2016, using a stationary bike, a treadmill, and resistance activities.
Researchers hoped Lecomte’s 159-day swim from June 5 to November 11, 2018, of 1,753 miles from Choshi, Japan, during which he averaged nearly six hours a day swimming, would keep his heart from shrinking and weakening.
Doctors performed various tests to measure the health and effectiveness of both Kelly’s and Lecomte’s hearts before, during, and after each man embarked on his respective expeditions.
The analysis found:
- Both Kelly and Lecomte lost mass from their left ventricles over the course of the experiences (Kelly 0.74 grams/week; Lecomte 0.72 grams/week).
- Both men suffered an initial drop in the diastolic diameter of their heart’s left ventricle (Kelly’s dropped from 5.3 to 4.6 cm; Lecomte’s reduced from 5 to 4.7 cm.).
- Even the most sustained periods of low-intensity exercise were not enough to counteract the effects of prolonged weightlessness.
- Left ventricle ejection fraction (LVEF) and markers of diastolic function did not consistently change in either individual throughout their campaign.
This case study examined two extraordinary feats by two unique individuals. While it is important to understand how the body responds to extreme circumstances, more study is required to understand how these results can be applied to the general population. Analysis of Lecomte’s cardiac MRIs from before and after his swim is forthcoming and will also be helpful for the researchers to further understand whether long-term effects of weightlessness can be reversed. Kelly did not receive cardiac MRIs, and currently, there are no further follow-up plans for him.