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Scientist – Polymorph Screening, API


Job Description:

Understanding the scope and strategy of polymorph screening project. Study of literature such as patents, research articles etc.
Determination of solubility, design of various screening methodologies and execution of crystallization experiments on High-Throughput Screening (HTS) platform. Reproducing discovered novel form(s) manually.
Identifying various crystallization processes for novel and/or open solid forms.
Preparation of amorphous forms with various methods. Stabilization of amorphous forms by preparing amorphous solid dispersions with various polymers using different methods.
Detailed characterization of solid forms with various analytical techniques such as PXRD, DSC/mDSC, TGA, FT-IR, KF, HPLC, GC, indexing PXRD etc. Novelty confirmation of crystalline forms.
Preparing necessary documentation for patent applications. Review of patent applications.
Preparing about 50-100g of targeted novel or open solid form(s) for stress, hygroscopic and 6-months stability studies.
Technical evaluation of equipments for procurement, coordination for installation, qualifications and necessary documentation.
SOPs preparation/revision as per need/schedule. Calibration of equipments as per schedule.
Documentation of reports and data archival. Effective implementation of eLN. Compliance to GLP.
Comprehensive risk assessment of drug substances. Ensuring safe handling of equipments, personnel and lab safety.

Technical Requirements:

-Experience on polymorph screening.
-Hands on experience on solid state analytical equipments such as PXRD, DSC, TGA etc and interpretation of results.
-Solid state problems solving skills.

Key Attributes:

-Self-starter, able to work independently with minimal supervision.
-Good communication and interpersonal skills.
-Willingness to learn.
-Good networking, able to coordinate and collaborate across multiple functional teams.
Salary: Not Disclosed by Recruiter
Industry: Pharma / Biotech / Clinical Research
Functional Area: Medical, Healthcare, R&D, Pharmaceuticals, Biotechnology
Role Category: Research Scientist
Role: Research Scientist


Polymorph Screeningsolid state analytical equipments such as PXRDDSCTGA

Desired Profile:

Education:UG -B.Sc – Chemistry, B.Pharma – Pharmacy
PG – M.Sc – Chemistry, M.Pharma – Pharmacy
Doctorate – Ph.D – Advertising/Mass Communication

Company Profile:

Dr. Reddy’s Laboratories Ltd. (NYSE: RDY) is an integrated global pharmaceutical company, committed to providing affordable and innovative medicines for healthier lives. Through its three businesses – Pharmaceutical Services and Active Ingredients, Global Generics and Proprietary Products – Dr. Reddy’s offers a portfolio of products and services including APIs, custom pharmaceutical services, generics, biosimilars and differentiated formulations. Major therapeutic focus is on gastro-intestinal, cardiovascular, diabetology, oncology, pain management and anti-infective. Major markets include India, USA, Russia-CIS and Europe apart from other select geographies within Emerging Markets. For more information, log on to:

Contact Details
Recruiter Name:Not Mentioned
Contact Company:Dr Reddys Laboratories Ltd
Telephone:Not Mentioned

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